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Within-host competition can delay evolution of drug resistance in malaria

In the malaria parasite P. falciparum, drug resistance generally evolves first in low-transmission settings, such as Southeast Asia and South America. Resistance takes noticeably longer to appear in the high-transmission settings of sub-Saharan Africa, although it may spread rapidly thereafter. Here...

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Detalles Bibliográficos
Autores principales: Bushman, Mary, Antia, Rustom, Udhayakumar, Venkatachalam, de Roode, Jacobus C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103507/
https://www.ncbi.nlm.nih.gov/pubmed/30130363
http://dx.doi.org/10.1371/journal.pbio.2005712