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Single-strand annealing between inverted DNA repeats: Pathway choice, participating proteins, and genome destabilizing consequences

Double strand DNA breaks (DSBs) are dangerous events that can result from various causes including environmental assaults or the collapse of DNA replication. While the efficient and precise repair of DSBs is essential for cell survival, faulty repair can lead to genetic instability, making the choic...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Sreejith, Kockler, Zachary, Evans, Robert, Downing, Brandon D., Malkova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103520/
https://www.ncbi.nlm.nih.gov/pubmed/30091972
http://dx.doi.org/10.1371/journal.pgen.1007543