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Single-strand annealing between inverted DNA repeats: Pathway choice, participating proteins, and genome destabilizing consequences
Double strand DNA breaks (DSBs) are dangerous events that can result from various causes including environmental assaults or the collapse of DNA replication. While the efficient and precise repair of DSBs is essential for cell survival, faulty repair can lead to genetic instability, making the choic...
Autores principales: | Ramakrishnan, Sreejith, Kockler, Zachary, Evans, Robert, Downing, Brandon D., Malkova, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103520/ https://www.ncbi.nlm.nih.gov/pubmed/30091972 http://dx.doi.org/10.1371/journal.pgen.1007543 |
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