Leukocyte Telomere Length Shortening, hTERT Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia

BACKGROUND: Telomeres are involved in chromosomal stability, cellular immortality and tumorigenesis. Human telomerase reverse transcriptase (TERT) is essential for the maintenance of telomere DNA length. Recently, a variable tandem-repeats polymorphism, MNS16A, located in the downstream region of th...

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Detalles Bibliográficos
Autores principales: Eskandari, Ebrahim, Hashemi, Mohammad, Naderi, Majid, Bahari, Gholamreza, Safdari, Vahid, Taheri, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103564/
https://www.ncbi.nlm.nih.gov/pubmed/29936725
http://dx.doi.org/10.22034/APJCP.2018.19.6.1515