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Transfer-RNA-mediated enhancement of ribosomal proteins S6 kinases signaling for cell proliferation

While transfer-RNAs (tRNAs) are known to transport amino acids to ribosome, new functions are being unveiled from tRNAs and their fragments beyond protein synthesis. Here we show that phosphorylation of 90-kDa RPS6K (ribosomal proteins S6 kinase) was enhanced by tRNA(Leu) overexpression under amino...

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Detalles Bibliográficos
Autores principales: Kwon, Nam Hoon, Lee, Mi Ran, Kong, Jiwon, Park, Seung Kyun, Hwang, Byung Joon, Kim, Byung Gyu, Lee, Eun-Shin, Moon, Hyeong-Gon, Kim, Sunghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103689/
https://www.ncbi.nlm.nih.gov/pubmed/28816616
http://dx.doi.org/10.1080/15476286.2017.1356563