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Transfer RNA instability as a stress response in Escherichia coli: Rapid dynamics of the tRNA pool as a function of demand

Production of the translation apparatus of E. coli is carefully matched to the demand for protein synthesis posed by a given growth condition. For example, the fraction of RNA polymerases that transcribe rRNA and tRNA drops from 80% during rapid growth to 24% within minutes of a sudden amino acid st...

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Detalles Bibliográficos
Autores principales: Sørensen, Michael Askvad, Fehler, Annaleigh Ohrt, Lo Svenningsen, Sine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103710/
https://www.ncbi.nlm.nih.gov/pubmed/29023189
http://dx.doi.org/10.1080/15476286.2017.1391440