A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo

Macroautophagy/autophagy is an evolutionarily conserved catabolic pathway whose modulation has been linked to diverse disease states, including age-associated disorders. Conventional and conditional whole-body knockout mouse models of key autophagy genes display perinatal death and lethal neurotoxic...

Descripción completa

Detalles Bibliográficos
Autores principales: Cassidy, Liam D., Young, Andrew RJ., Pérez-Mancera, Pedro A., Nimmervoll, Birgit, Jaulim, Adil, Chen, Hung-Chang, McIntyre, Dominick J. O., Brais, Rebecca, Ricketts, Thomas, Pacey, Simon, De La Roche, Maike, Gilbertson, Richard J., Rubinsztein, David C., Narita, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Toolbox
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103714/
https://www.ncbi.nlm.nih.gov/pubmed/29999454
http://dx.doi.org/10.1080/15548627.2018.1458172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103714/
https://www.ncbi.nlm.nih.gov/pubmed/29999454
http://dx.doi.org/10.1080/15548627.2018.1458172

Ejemplares similares