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Influence of sample collection tube method, anticoagulant-containing plasma versus serum, on influenza virus hemagglutination inhibition titer and microneutralization titer serological assays

BACKGROUND: The hemagglutination-inhibition (HAI) assay is a critical component for measurement of immunogenicity in influenza vaccine development. It is unknown if the results can be influenced by sample type and anticoagulants. The purpose of this study was to evaluate the influence of different s...

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Detalles Bibliográficos
Autores principales: Morrison, Brian J., Martin, Nicholas J., Rehman, Tauseef, Ewing, Dan, Dewar, Robin L., Metcalf, Julia, Sun, Peifang, Beigel, John, Luke, Thomas C., Raviprakash, Kanakatte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103864/
https://www.ncbi.nlm.nih.gov/pubmed/30134892
http://dx.doi.org/10.1186/s12913-018-3465-3