Cargando…
Simple deep sequencing-based post-remission MRD surveillance predicts clinical relapse in B-ALL
BACKGROUND: Next-generation sequencing (NGS) of the rearranged immunoglobulin heavy-chain gene has emerged as a highly sensitive method to detect minimal residual disease (MRD) in B acute lymphoblastic leukemia/lymphoma (B-ALL). However, a sensitive and easily implemented NGS methodology for routine...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103872/ https://www.ncbi.nlm.nih.gov/pubmed/30134947 http://dx.doi.org/10.1186/s13045-018-0652-y |