Simple deep sequencing-based post-remission MRD surveillance predicts clinical relapse in B-ALL

BACKGROUND: Next-generation sequencing (NGS) of the rearranged immunoglobulin heavy-chain gene has emerged as a highly sensitive method to detect minimal residual disease (MRD) in B acute lymphoblastic leukemia/lymphoma (B-ALL). However, a sensitive and easily implemented NGS methodology for routine...

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Detalles Bibliográficos
Autores principales: Cheng, Shuhua, Inghirami, Giorgio, Cheng, Shuo, Tam, Wayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103872/
https://www.ncbi.nlm.nih.gov/pubmed/30134947
http://dx.doi.org/10.1186/s13045-018-0652-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103872/
https://www.ncbi.nlm.nih.gov/pubmed/30134947
http://dx.doi.org/10.1186/s13045-018-0652-y

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