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Simple deep sequencing-based post-remission MRD surveillance predicts clinical relapse in B-ALL
BACKGROUND: Next-generation sequencing (NGS) of the rearranged immunoglobulin heavy-chain gene has emerged as a highly sensitive method to detect minimal residual disease (MRD) in B acute lymphoblastic leukemia/lymphoma (B-ALL). However, a sensitive and easily implemented NGS methodology for routine...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103872/ https://www.ncbi.nlm.nih.gov/pubmed/30134947 http://dx.doi.org/10.1186/s13045-018-0652-y |