High-dose intravenous immunoglobulins reduce nerve macrophage infiltration and the severity of bortezomib-induced peripheral neurotoxicity in rats

BACKGROUND: Chemotherapy-induced peripheral neurotoxicity (CIPN) is a severe adverse effect in patients receiving antitumor agents, and no effective treatment is available. Although the mechanisms responsible for the development of CIPN are poorly understood, recent findings make neuroinflammation a...

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Detalles Bibliográficos
Autores principales: Meregalli, Cristina, Marjanovic, Ivan, Scali, Carla, Monza, Laura, Spinoni, Nadia, Galliani, Cristina, Brivio, Rinaldo, Chiorazzi, Alessia, Ballarini, Elisa, Rodriguez-Menendez, Virginia, Carozzi, Valentina Alda, Alberti, Paola, Fumagalli, Giulia, Pozzi, Eleonora, Canta, Annalisa, Quartu, Marina, Briani, Chiara, Oggioni, Norberto, Marmiroli, Paola, Cavaletti, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103882/
https://www.ncbi.nlm.nih.gov/pubmed/30131066
http://dx.doi.org/10.1186/s12974-018-1270-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103882/
https://www.ncbi.nlm.nih.gov/pubmed/30131066
http://dx.doi.org/10.1186/s12974-018-1270-x

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