Mutagenic properties of dimethylaniline isomers in mice as evaluated by comet, micronucleus and transgenic mutation assays

BACKGROUND: The carcinogenic potential of dimethylaniline (DMA) isomers in rodents and humans has been previously reported, and there is sufficient evidence for the carcinogenicity of 2,6-DMA in experimental animals. The target organ of carcinogenesis of 2,6-DMA is the nasal cavity. In the current s...

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Detalles Bibliográficos
Autores principales: Kohara, Arihiro, Matsumoto, Mariko, Hirose, Akihiko, Hayashi, Makoto, Honma, Masamitsu, Suzuki, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103965/
https://www.ncbi.nlm.nih.gov/pubmed/30151062
http://dx.doi.org/10.1186/s41021-018-0106-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103965/
https://www.ncbi.nlm.nih.gov/pubmed/30151062
http://dx.doi.org/10.1186/s41021-018-0106-3

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