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Mutagenic properties of dimethylaniline isomers in mice as evaluated by comet, micronucleus and transgenic mutation assays
BACKGROUND: The carcinogenic potential of dimethylaniline (DMA) isomers in rodents and humans has been previously reported, and there is sufficient evidence for the carcinogenicity of 2,6-DMA in experimental animals. The target organ of carcinogenesis of 2,6-DMA is the nasal cavity. In the current s...
Autores principales: | Kohara, Arihiro, Matsumoto, Mariko, Hirose, Akihiko, Hayashi, Makoto, Honma, Masamitsu, Suzuki, Takayoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103965/ https://www.ncbi.nlm.nih.gov/pubmed/30151062 http://dx.doi.org/10.1186/s41021-018-0106-3 |
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