Proteomic characterization of endogenous substrates of mammalian ubiquitin ligase Hrd1

BACKGROUND: Endoplasmic reticulum (ER)-associated degradation (ERAD) regulates protein homeostasis in the secretory pathway by targeting misfolded or unassembled proteins for degradation by the proteasome. Hrd1 is a conserved multi-spanning membrane bound ubiquitin ligase required for ubiquitination...

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Detalles Bibliográficos
Autores principales: Ye, Yilin, Baek, Suk-Hwan, Ye, Yihong, Zhang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103995/
https://www.ncbi.nlm.nih.gov/pubmed/30167107
http://dx.doi.org/10.1186/s13578-018-0245-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103995/
https://www.ncbi.nlm.nih.gov/pubmed/30167107
http://dx.doi.org/10.1186/s13578-018-0245-z

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