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Design considerations for early-phase clinical trials of immune-oncology agents
BACKGROUND: With numerous and fast approvals of different agents including immune checkpoint inhibitors, monoclonal antibodies, or chimeric antigen receptor (CAR) T-cell therapy, immunotherapy is now an established form of cancer treatment. These agents have demonstrated impressive clinical activity...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103998/ https://www.ncbi.nlm.nih.gov/pubmed/30134959 http://dx.doi.org/10.1186/s40425-018-0389-8 |