Nanoscale Peptide Self-assemblies Boost BCG-primed Cellular Immunity Against Mycobacterium tuberculosis

Bacillus Calmette-Guerin (BCG) is the only vaccine against TB and has limited protection efficacy, which wanes past adolescence. Multifunctional CD8+ T cells (IFN-γ+/TNF-α+/IL-2+) are associated with lower reactivation risk and enhanced control of active Mtb infection. Since boosting with BCG is con...

Descripción completa

Detalles Bibliográficos
Autores principales: Chesson, Charles B., Huante, Matthew, Nusbaum, Rebecca J., Walker, Aida G., Clover, Tara M., Chinnaswamy, Jagannath, Endsley, Janice J., Rudra, Jai S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104033/
https://www.ncbi.nlm.nih.gov/pubmed/30131591
http://dx.doi.org/10.1038/s41598-018-31089-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104033/
https://www.ncbi.nlm.nih.gov/pubmed/30131591
http://dx.doi.org/10.1038/s41598-018-31089-y

Ejemplares similares