Cargando…

Drug treatment efficiency depends on the initial state of activation in nonlinear pathways

An accurate prediction of the outcome of a given drug treatment requires quantitative values for all parameters and concentrations involved as well as a detailed characterization of the network of interactions where the target molecule is embedded. Here, we present a high-throughput in silico screen...

Descripción completa

Detalles Bibliográficos
Autores principales: Doldán-Martelli, Victoria, Míguez, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104077/
https://www.ncbi.nlm.nih.gov/pubmed/30131510
http://dx.doi.org/10.1038/s41598-018-30913-9