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Drug treatment efficiency depends on the initial state of activation in nonlinear pathways
An accurate prediction of the outcome of a given drug treatment requires quantitative values for all parameters and concentrations involved as well as a detailed characterization of the network of interactions where the target molecule is embedded. Here, we present a high-throughput in silico screen...
Autores principales: | Doldán-Martelli, Victoria, Míguez, David G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104077/ https://www.ncbi.nlm.nih.gov/pubmed/30131510 http://dx.doi.org/10.1038/s41598-018-30913-9 |
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