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Metal-free alcohol-directed regioselective heteroarylation of remote unactivated C(sp(3))–H bonds

Construction of C–C bonds via alkoxy radical-mediated remote C(sp(3))–H functionalization is largely unexplored, as it is a formidable challenge to directly generate alkoxy radicals from alcohols due to the high bond dissociation energy (BDE) of O–H bonds. Disclosed herein is a practical and elusive...

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Detalles Bibliográficos
Autores principales:	Wu, Xinxin, Zhang, Hong, Tang, Nana, Wu, Zhen, Wang, Dongping, Ji, Meishan, Xu, Yan, Wang, Min, Zhu, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104081/ https://www.ncbi.nlm.nih.gov/pubmed/30131495 http://dx.doi.org/10.1038/s41467-018-05522-9

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