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Ranitidine Inhibition of Breast Tumor Growth Is B Cell Dependent and Associated With an Enhanced Antitumor Antibody Response

BACKGROUND: The histamine receptor 2 antagonist ranitidine is a commonly used, non-prescription, medication. It limits the development, growth, and metastasis of breast cancers in mouse models of disease. In this study, we examined the role of B cells in this response, the impact of ranitidine on th...

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Detalles Bibliográficos
Autores principales: Rogers, Dakota, Vila-Leahey, Ava, Pessôa, Ana Clara, Oldford, Sharon, Marignani, Paola A., Marshall, Jean S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104125/
https://www.ncbi.nlm.nih.gov/pubmed/30158936
http://dx.doi.org/10.3389/fimmu.2018.01894