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Quantitation of tadalafil in human plasma using a sensitive and rapid LC-MS/MS method for a bioequivalence study

A highly sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the determination of tadalafil (TAD) in human plasma. TAD and its deuterated internal standard (IS), tadalafil-d3, were extracted from 200 µL plasma using Phenomenex Strata-X-C 33 µ extraction cartr...

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Detalles Bibliográficos
Autores principales: Bhadoriya, Abhaysingh, Dasandi, Bhavesh, Parmar, Dharmesh, Shah, Priyanka A., Shrivastav, Pranav S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104147/
https://www.ncbi.nlm.nih.gov/pubmed/30140492
http://dx.doi.org/10.1016/j.jpha.2018.01.003