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Sulbactam Protects Hippocampal Neurons Against Oxygen-Glucose Deprivation by Up-Regulating Astrocytic GLT-1 via p38 MAPK Signal Pathway

Sulbactam is an atypical β-lactam medication and reported to be neuroprotective by up-regulating glial glutamate transporter-1 (GLT-1) in rats. The present study was undertaken to study the role of p38 MAPK signal pathway in sulbactam induced up-regulation of GLT-1 expression in astrocytes and anti-...

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Detalles Bibliográficos
Autores principales: Qi, Jie, Xian, Xiao-Hui, Li, Li, Zhang, Min, Hu, Yu-Yan, Zhang, Jing-Ge, Li, Wen-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104165/
https://www.ncbi.nlm.nih.gov/pubmed/30158854
http://dx.doi.org/10.3389/fnmol.2018.00281