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STAT3 Cooperates With Phospholipid Scramblase 2 to Suppress Type I Interferon Response

Type I interferon (IFN-I) is a pluripotent cytokine that modulates innate and adaptive immunity. We have previously shown that STAT3 suppresses IFN-I response in a manner dependent on its N-terminal domain (NTD), but independent of its DNA-binding and transactivation ability. Using the yeast two-hyb...

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Detalles Bibliográficos
Autores principales: Tsai, Ming-Hsun, Lee, Chien-Kuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104169/
https://www.ncbi.nlm.nih.gov/pubmed/30158934
http://dx.doi.org/10.3389/fimmu.2018.01886