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STAT3 Cooperates With Phospholipid Scramblase 2 to Suppress Type I Interferon Response
Type I interferon (IFN-I) is a pluripotent cytokine that modulates innate and adaptive immunity. We have previously shown that STAT3 suppresses IFN-I response in a manner dependent on its N-terminal domain (NTD), but independent of its DNA-binding and transactivation ability. Using the yeast two-hyb...
Autores principales: | Tsai, Ming-Hsun, Lee, Chien-Kuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104169/ https://www.ncbi.nlm.nih.gov/pubmed/30158934 http://dx.doi.org/10.3389/fimmu.2018.01886 |
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