Intermittent Hypoxia Mimicking Sleep Apnea Increases Passive Stiffness of Myocardial Extracellular Matrix. A Multiscale Study

Background: Tissue hypoxia-reoxygenation characterizes obstructive sleep apnea (OSA), a very prevalent respiratory disease associated with increased cardiovascular morbidity and mortality. Experimental studies indicate that intermittent hypoxia (IH) mimicking OSA induces oxidative stress and inflamm...

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Detalles Bibliográficos
Autores principales: Farré, Núria, Otero, Jorge, Falcones, Bryan, Torres, Marta, Jorba, Ignasi, Gozal, David, Almendros, Isaac, Farré, Ramon, Navajas, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104184/
https://www.ncbi.nlm.nih.gov/pubmed/30158879
http://dx.doi.org/10.3389/fphys.2018.01143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104184/
https://www.ncbi.nlm.nih.gov/pubmed/30158879
http://dx.doi.org/10.3389/fphys.2018.01143

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