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Identification of four families of yCCR4- and Mg(2+)-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding

BACKGROUND: The yeast yCCR4 factor belongs to the CCR4-NOT transcriptional regulatory complex, in which it interacts, through its leucine-rich repeat (LRR) motif with yPOP2. Recently, yCCR4 was shown to be a component of the major cytoplasmic mRNA deadenylase complex, and to contain a fold related t...

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Detalles Bibliográficos
Autores principales: Dupressoir, Anne, Morel, Anne-Pierre, Barbot, Willy, Loireau, Marie-Paule, Corbo, Laura, Heidmann, Thierry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC61044/
https://www.ncbi.nlm.nih.gov/pubmed/11747467
http://dx.doi.org/10.1186/1471-2164-2-9