SAHAquines, Novel Hybrids Based on SAHA and Primaquine Motifs, as Potential Cytostatic and Antiplasmodial Agents

We report the synthesis of SAHAquines and related primaquine (PQ) derivatives. SAHAquines are novel hybrid compounds that combine moieties of suberoylanilide hydroxamic acid (SAHA), an anticancer agent with weak antiplasmodial activity, and PQ, an antimalarial drug with low antiproliferative activit...

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Detalles Bibliográficos
Autores principales: Beus, Maja, Rajić, Zrinka, Maysinger, Dusica, Mlinarić, Zvonimir, Antunović, Maja, Marijanović, Inga, Fontinha, Diana, Prudêncio, Miguel, Held, Jana, Olgen, Sureyya, Zorc, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104433/
https://www.ncbi.nlm.nih.gov/pubmed/30151334
http://dx.doi.org/10.1002/open.201800117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104433/
https://www.ncbi.nlm.nih.gov/pubmed/30151334
http://dx.doi.org/10.1002/open.201800117

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