CARMA3 Is a Critical Mediator of G Protein-Coupled Receptor and Receptor Tyrosine Kinase-Driven Solid Tumor Pathogenesis

The CARMA–Bcl10–MALT1 (CBM) signalosome is an intracellular protein complex composed of a CARMA scaffolding protein, the Bcl10 linker protein, and the MALT1 protease. This complex was first recognized because the genes encoding its components are targeted by mutation and chromosomal translocation in...

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Detalles Bibliográficos
Autores principales: McAuley, J. Randall, Freeman, Tanner J., Ekambaram, Prasanna, Lucas, Peter C., McAllister-Lucas, Linda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104486/
https://www.ncbi.nlm.nih.gov/pubmed/30158935
http://dx.doi.org/10.3389/fimmu.2018.01887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104486/
https://www.ncbi.nlm.nih.gov/pubmed/30158935
http://dx.doi.org/10.3389/fimmu.2018.01887

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