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Coordination of Necessary and Permissive Signals by PTEN Inhibition for CNS Axon Regeneration
In the nearly 10 years since PTEN was identified as a prominent intrinsic inhibitor of CNS axon regeneration, the PTEN negatively regulated PI3K-AKT-mTOR pathway has been intensively explored in diverse models of axon injury and diseases and its mechanism for axon regeneration is becoming clearer. I...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104488/ https://www.ncbi.nlm.nih.gov/pubmed/30158848 http://dx.doi.org/10.3389/fnins.2018.00558 |