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Coordination of Necessary and Permissive Signals by PTEN Inhibition for CNS Axon Regeneration

In the nearly 10 years since PTEN was identified as a prominent intrinsic inhibitor of CNS axon regeneration, the PTEN negatively regulated PI3K-AKT-mTOR pathway has been intensively explored in diverse models of axon injury and diseases and its mechanism for axon regeneration is becoming clearer. I...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Yang, Dakai, Huang, Haoliang, Sun, Yang, Hu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104488/
https://www.ncbi.nlm.nih.gov/pubmed/30158848
http://dx.doi.org/10.3389/fnins.2018.00558