Micro-RNA-137 Inhibits Tau Hyperphosphorylation in Alzheimer’s Disease and Targets the CACNA1C Gene in Transgenic Mice and Human Neuroblastoma SH-SY5Y Cells

BACKGROUND: Alzheimer’s disease (AD) results in cognitive impairment. The calcium voltage-gated channel subunit alpha-1 C CACNA1C gene encodes an alpha-1 C subunit of L-type calcium channel (LTCC). The aim of this study was to investigate the role of micro-RNA-137 (miR-137) and the CACNA1C gene in A...

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Detalles Bibliográficos
Autores principales: Jiang, Yang, Xu, Bing, Chen, Jing, Sui, Yi, Ren, Li, Li, Jing, Zhang, Huiyu, Guo, Liqing, Sun, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104547/
https://www.ncbi.nlm.nih.gov/pubmed/30102687
http://dx.doi.org/10.12659/MSM.908765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104547/
https://www.ncbi.nlm.nih.gov/pubmed/30102687
http://dx.doi.org/10.12659/MSM.908765

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