An Observational Study from Long-Term AAV Re-administration in Two Hemophilia Dogs

Adeno-associated virus (AAV) vectors have been successfully applied in hemophilia clinical trials. However, this approach is limited to patients without AAV-neutralizing antibodies (NAbs). In this study, we explored the feasibility of AAV re-administration in hemophilia A dogs treated initially 8 ye...

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Detalles Bibliográficos
Autores principales: Sun, Junjiang, Shao, Wenwei, Chen, Xiaojing, Merricks, Elizabeth P., Wimsey, Lauren, Abajas, Yasmina L., Niemeyer, Glenn P., Lothrop, Clinton D., Monahan, Paul E., Samulski, R. Jude, Nichols, Timothy C., Li, Chengwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104583/
https://www.ncbi.nlm.nih.gov/pubmed/30140713
http://dx.doi.org/10.1016/j.omtm.2018.07.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104583/
https://www.ncbi.nlm.nih.gov/pubmed/30140713
http://dx.doi.org/10.1016/j.omtm.2018.07.011

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