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Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase

Sialidases are key virulence factors that remove sialic acid from the host cell surface glycan, unmasking receptors that facilitate bacterial adherence and colonisation. In this study, we developed potential agents for treating bacterial infections caused by Streptococcus pneumoniae Nan A that inhib...

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Detalles Bibliográficos
Autores principales: Kim, Bo Ram, Park, Ji-Young, Jeong, Hyung Jae, Kwon, Hyung-Jun, Park, Su-Jin, Lee, In-Chul, Ryu, Young Bae, Lee, Woo Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104608/
https://www.ncbi.nlm.nih.gov/pubmed/30126306
http://dx.doi.org/10.1080/14756366.2018.1488695