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Design, synthesis, and evaluation of curcumin analogues as potential inhibitors of bacterial sialidase
Sialidases are key virulence factors that remove sialic acid from the host cell surface glycan, unmasking receptors that facilitate bacterial adherence and colonisation. In this study, we developed potential agents for treating bacterial infections caused by Streptococcus pneumoniae Nan A that inhib...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104608/ https://www.ncbi.nlm.nih.gov/pubmed/30126306 http://dx.doi.org/10.1080/14756366.2018.1488695 |