Number of individual ACPA reactivities in synovial fluid immune complexes, but not serum anti-CCP2 levels, associate with inflammation and joint destruction in rheumatoid arthritis

INTRODUCTION: Individual patients with rheumatoid arthritis (RA) show divergent specific anti-citrullinated protein/peptide antibodies (ACPA) patterns, but hitherto no individual ACPA specificity has consistently been linked to RA pathogenesis. ACPA are also implicated in immune complexes (IC)-assoc...

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Detalles Bibliográficos
Autores principales: Sohrabian, Azita, Mathsson-Alm, Linda, Hansson, Monika, Knight, Ann, Lysholm, Jörgen, Cornillet, Martin, Skriner, Karl, Serre, Guy, Larsson, Anders, Weitoft, Tomas, Rönnelid, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104681/
https://www.ncbi.nlm.nih.gov/pubmed/29895567
http://dx.doi.org/10.1136/annrheumdis-2017-212627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104681/
https://www.ncbi.nlm.nih.gov/pubmed/29895567
http://dx.doi.org/10.1136/annrheumdis-2017-212627

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