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Aminoacyl-tRNA synthetase evolution and sectoring of the genetic code

The genetic code sectored via tRNA charging errors, and the code progressed toward closure and universality because of evolution of aminoacyl-tRNA synthetase (aaRS) fidelity and translational fidelity mechanisms. Class I and class II aaRS folds are identified as homologs. From sequence alignments, a...

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Detalles Bibliográficos
Autores principales: Pak, Daewoo, Kim, Yunsoo, Burton, Zachary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104698/
https://www.ncbi.nlm.nih.gov/pubmed/29727262
http://dx.doi.org/10.1080/21541264.2018.1467718