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Lipid bilayer-atomic force microscopy combined platform records simultaneous electrical and topological changes of the TRP channel polycystin-2 (TRPP2)

Ion channels are transmembrane proteins that mediate ion transport across biological membranes. Ion channel function is traditionally characterized by electrical parameters acquired with techniques such as patch-clamping and reconstitution in lipid bilayer membranes (BLM) that provide relevant infor...

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Detalles Bibliográficos
Autores principales: Lal, Sumit, Scarinci, Noelia, Perez, Paula L., Cantero, María del Rocío, Cantiello, Horacio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104948/
https://www.ncbi.nlm.nih.gov/pubmed/30133487
http://dx.doi.org/10.1371/journal.pone.0202029