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Case-control studies of gene-environment interactions. When a case might not be the case

Case-control Genome-Wide Association Studies (GWAS) provide a rich resource for studying the genetic architecture of complex diseases. A key is to elucidate how the genetic effects vary by the environment, what is traditionally defined by Gene-Environment interactions (GxE). The overlooked complicat...

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Detalles Bibliográficos
Autores principales: Lobach, Iryna, Sampson, Joshua, Alekseyenko, Alexander, Lobach, Siarhei, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104951/
https://www.ncbi.nlm.nih.gov/pubmed/30133451
http://dx.doi.org/10.1371/journal.pone.0201140