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A mathematical model for the effects of amyloid beta on intracellular calcium
The accumulation of Alzheimer’s disease (AD) associated Amyloid beta (Aβ) oligomers can trigger aberrant intracellular calcium (Ca(2+)) levels by disrupting the intrinsic Ca(2+) regulatory mechanism within cells. These disruptions can cause changes in homeostasis levels that can have detrimental eff...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105003/ https://www.ncbi.nlm.nih.gov/pubmed/30133494 http://dx.doi.org/10.1371/journal.pone.0202503 |