The crystal structure of KSHV ORF57 reveals dimeric active sites important for protein stability and function

Kaposi’s sarcoma-associated herpesvirus (KSHV) is a γ-herpesvirus closely associated with Kaposi’s sarcoma, primary effusion lymphoma and multicentric Castleman disease. Open reading frame 57 (ORF57), a viral early protein of KSHV promotes splicing, stability and translation of viral mRNA and is ess...

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Detalles Bibliográficos
Autores principales: Yuan, Fei, Gao, Zeng-Qiang, Majerciak, Vladimir, Bai, Lei, Hu, Meng-Lu, Lin, Xiao-Xi, Zheng, Zhi-Ming, Dong, Yu-Hui, Lan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105031/
https://www.ncbi.nlm.nih.gov/pubmed/30096191
http://dx.doi.org/10.1371/journal.ppat.1007232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105031/
https://www.ncbi.nlm.nih.gov/pubmed/30096191
http://dx.doi.org/10.1371/journal.ppat.1007232

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