Patched-2 functions to limit Patched-1 deficient skin cancer growth

PURPOSE: Basal cell carcinoma (BCC) is one of the most common skin cancers, and is typically driven by an aberrantly activated Hedgehog (Hh) pathway. The Hh pathway is regulated by interactions between the Patched-1 (Ptch1) and Smoothened (Smo) receptors. Smo is an activating receptor and is subject...

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Detalles Bibliográficos
Autores principales: Veenstra, Veronique L., Dingjan, Ilse, Waasdorp, Cynthia, Damhofer, Helene, van der Wal, Allard C., van Laarhoven, Hanneke W., Medema, Jan Paul, Bijlsma, Maarten F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105176/
https://www.ncbi.nlm.nih.gov/pubmed/29869097
http://dx.doi.org/10.1007/s13402-018-0381-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105176/
https://www.ncbi.nlm.nih.gov/pubmed/29869097
http://dx.doi.org/10.1007/s13402-018-0381-9

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