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Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Curtailed sleep promotes weight gain and loss of lean mass in humans, although the underlying molecular mechanisms are poorly understood. We investigated the genomic and physiological impact of acute sleep loss in peripheral tissues by obtaining adipose tissue and skeletal muscle after one night of...

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Detalles Bibliográficos
Autores principales: Cedernaes, Jonathan, Schönke, Milena, Westholm, Jakub Orzechowski, Mi, Jia, Chibalin, Alexander, Voisin, Sarah, Osler, Megan, Vogel, Heike, Hörnaeus, Katarina, Dickson, Suzanne L., Lind, Sara Bergström, Bergquist, Jonas, Schiöth, Helgi B, Zierath, Juleen R., Benedict, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105229/
https://www.ncbi.nlm.nih.gov/pubmed/30140739
http://dx.doi.org/10.1126/sciadv.aar8590