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Concerted Nucleophilic Aromatic Substitutions

Nucleophilic aromatic substitution (S(N)Ar) is one of the most widely applied reaction classes in pharmaceutical and chemical research, providing a broadly useful platform for the modification of aromatic ring scaffolds. The generally accepted mechanism for S(N)Ar reactions involves a two-step addit...

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Detalles Bibliográficos
Autores principales: Kwan, Eugene E., Zeng, Yuwen, Besser, Harrison A., Jacobsen, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105541/
https://www.ncbi.nlm.nih.gov/pubmed/30013193
http://dx.doi.org/10.1038/s41557-018-0079-7