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Concerted Nucleophilic Aromatic Substitutions
Nucleophilic aromatic substitution (S(N)Ar) is one of the most widely applied reaction classes in pharmaceutical and chemical research, providing a broadly useful platform for the modification of aromatic ring scaffolds. The generally accepted mechanism for S(N)Ar reactions involves a two-step addit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105541/ https://www.ncbi.nlm.nih.gov/pubmed/30013193 http://dx.doi.org/10.1038/s41557-018-0079-7 |