Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity

Uptake of tumor antigens by tumor-infiltrating dendritic cells is limiting step in the induction of tumor immunity, which can be mediated through Fc receptor (FcR) triggering by antibody-coated tumor cells. Here we describe an approach to potentiate tumor immunity whereby hapten-specific polyclonal...

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Detalles Bibliográficos
Autores principales: Schrand, Brett, Clark, Emily, Levay, Agata, Capote, Ailem Rabasa, Martinez, Olivier, Brenneman, Randall, Castro, Iris, Gilboa, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105580/
https://www.ncbi.nlm.nih.gov/pubmed/30135425
http://dx.doi.org/10.1038/s41467-018-05566-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105580/
https://www.ncbi.nlm.nih.gov/pubmed/30135425
http://dx.doi.org/10.1038/s41467-018-05566-x

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