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Hapten-mediated recruitment of polyclonal antibodies to tumors engenders antitumor immunity
Uptake of tumor antigens by tumor-infiltrating dendritic cells is limiting step in the induction of tumor immunity, which can be mediated through Fc receptor (FcR) triggering by antibody-coated tumor cells. Here we describe an approach to potentiate tumor immunity whereby hapten-specific polyclonal...
Autores principales: | Schrand, Brett, Clark, Emily, Levay, Agata, Capote, Ailem Rabasa, Martinez, Olivier, Brenneman, Randall, Castro, Iris, Gilboa, Eli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105580/ https://www.ncbi.nlm.nih.gov/pubmed/30135425 http://dx.doi.org/10.1038/s41467-018-05566-x |
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