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Optical Characterization of Neurosurgical Operating Microscopes: Quantitative Fluorescence and Assessment of PpIX Photobleaching

Protoporphyrin IX (PpIX) induced by 5-aminolevulinic acid (5-ALA) is increasingly used as a fluorescent marker for fluorescence-guided resection of malignant gliomas. Understanding how the properties of the excitation light source and PpIX fluorescence interact with the surgical microscope is critic...

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Detalles Bibliográficos
Autores principales: Belykh, Evgenii, Miller, Eric J., Patel, Arpan A., Bozkurt, Baran, Yağmurlu, Kaan, Robinson, Timothy R., Nakaji, Peter, Spetzler, Robert F., Lawton, Michael T., Nelson, Leonard Y., Seibel, Eric J., Preul, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105612/
https://www.ncbi.nlm.nih.gov/pubmed/30135440
http://dx.doi.org/10.1038/s41598-018-30247-6