Functional diversity of TMPRSS6 isoforms and variants expressed in hepatocellular carcinoma cell lines

TMPRSS6, also known as matriptase-2, is a type II transmembrane serine protease that plays a major role in iron homeostasis by acting as a negative regulator of hepcidin production through cleavage of the BMP co-receptor haemojuvelin. Iron-refractory iron deficiency anaemia (IRIDA), an iron metaboli...

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Detalles Bibliográficos
Autores principales: Dion, Sébastien P., Béliveau, François, Morency, Louis-Philippe, Désilets, Antoine, Najmanovich, Rafaël, Leduc, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105633/
https://www.ncbi.nlm.nih.gov/pubmed/30135444
http://dx.doi.org/10.1038/s41598-018-30618-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105633/
https://www.ncbi.nlm.nih.gov/pubmed/30135444
http://dx.doi.org/10.1038/s41598-018-30618-z

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