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Functional diversity of TMPRSS6 isoforms and variants expressed in hepatocellular carcinoma cell lines
TMPRSS6, also known as matriptase-2, is a type II transmembrane serine protease that plays a major role in iron homeostasis by acting as a negative regulator of hepcidin production through cleavage of the BMP co-receptor haemojuvelin. Iron-refractory iron deficiency anaemia (IRIDA), an iron metaboli...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105633/ https://www.ncbi.nlm.nih.gov/pubmed/30135444 http://dx.doi.org/10.1038/s41598-018-30618-z |