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Improvement of vascular dysfunction by argirein through inhibiting endothelial cell apoptosis associated with ET-1/Nox4 signal pathway in diabetic rats

Endothelial cell apoptosis plays an important role in the pathophysiological mechanism of vascular complications in type 2 diabetes mellitus (T2DM). Argirein, a new synthetic compound was demonstrated to inactivate NADPH oxidase to alleviate cardiac dysfunction in T2DM. Here, we investigated whether...

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Detalles Bibliográficos
Autores principales: Su, Jie, An, Xing-Rong, Li, Qing, Li, Xiao-Xue, Cong, Xiao-dong, Xu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105644/
https://www.ncbi.nlm.nih.gov/pubmed/30135489
http://dx.doi.org/10.1038/s41598-018-30386-w