Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies

Currently available influenza virus vaccines have inadequate effectiveness and are reformulated annually due to viral antigenic drift. Thus, development of a vaccine that confers long-term protective immunity against antigenically distant influenza virus strains is urgently needed. The highly conser...

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Detalles Bibliográficos
Autores principales: Pardi, Norbert, Parkhouse, Kaela, Kirkpatrick, Ericka, McMahon, Meagan, Zost, Seth J., Mui, Barbara L., Tam, Ying K., Karikó, Katalin, Barbosa, Christopher J., Madden, Thomas D., Hope, Michael J., Krammer, Florian, Hensley, Scott E., Weissman, Drew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105651/
https://www.ncbi.nlm.nih.gov/pubmed/30135514
http://dx.doi.org/10.1038/s41467-018-05482-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105651/
https://www.ncbi.nlm.nih.gov/pubmed/30135514
http://dx.doi.org/10.1038/s41467-018-05482-0

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